Description

Cyclobutaneacetic Acid, α-Amino-1-Mercapto- (9Ci) is a specialized chiral building block featuring a unique cyclobutane ring system combined with amino and mercapto functional groups. This compound is valued for its structural complexity and potential as a key intermediate in advanced synthetic chemistry, enabling the construction of novel molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel drug candidates, particularly for constructing constrained peptide mimetics and bioactive small molecules.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclobutane scaffold can impart specific biological activity and stability.
• Peptidomimetics Research: The amino and thiol functionalities make it a valuable precursor for designing and synthesizing conformationally restricted peptide analogs.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of novel chelating ligands and asymmetric catalysts.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and protein interactions due to its reactive thiol group.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Cyclobutaneacetic Acid, α-Amino-1-Mercapto- (9Ci)
CAS No.	756765-00-1
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	2-Amino-2-mercaptocyclobutaneacetic acid; α-Amino-α-mercaptocyclobutaneacetic acid; (2-Amino-2-sulfanylcyclobutyl)acetic acid; 1-Amino-1-mercaptocyclobutane-1-acetic acid; Cyclobutaneacetic acid, α-amino-α-mercapto-; 756765-00-1; (Aminomercapto)cyclobutylacetic acid
EINECS	Contact for details

Quality Control

Our Cyclobutaneacetic Acid, α-Amino-1-Mercapto- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. This product is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use and stored in a cool, dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.