Description

1-Chloro-2-Iodo-4,5-Dimethylbenzene is a halogenated aromatic compound with a unique substitution pattern, serving as a versatile and valuable building block in advanced organic synthesis. Its distinct molecular structure makes it particularly useful for introducing sterically hindered halogen functionalities into complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as in materials science for creating specialized polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting complex aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its halogenated structure can contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialized organic electronic materials and liquid crystal display (LCD) components.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings, enabling the construction of complex biaryl systems.
• Organic Synthesis Building Block: Provides a sterically defined, di-substituted benzene core for further functionalization in academic and industrial R&D laboratories.
• Chemical Research & Development: Employed as a standard or reference compound in method development and catalytic studies involving halogenated aromatics.

Basic Information

Product Name	1-Chloro-2-Iodo-4,5-Dimethylbenzene
CAS No.	755758-89-5
Molecular Formula	C8H8ClI
Molecular Weight	266.51 g/mol
Synonyms	2-Chloro-1-iodo-4,5-dimethylbenzene; 4,5-Dimethyl-1-chloro-2-iodobenzene; 1-Chloro-2-iodo-4,5-dimethylbenzene; 4,5-Dimethyl-2-chloroiodobenzene; 2-Chloro-4,5-dimethyl-1-iodobenzene; 1-Iodo-2-chloro-4,5-dimethylbenzene; Benzene, 1-chloro-2-iodo-4,5-dimethyl-
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-Iodo-4,5-Dimethylbenzene is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the exacting requirements of research and industrial synthesis. A detailed Certificate of Analysis (COA) providing purity, identity confirmation, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.