Description

3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,(3R)-(9Ci) is a chiral, tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for pharmaceutical research, particularly in the development of active pharmaceutical ingredients (APIs) and chiral ligands. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate a structurally complex, stereochemically defined moiety into novel molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential therapeutic agents targeting neurological and cardiovascular diseases.
• Asymmetric Catalyst Ligand: Utilized in the development of novel chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Agrochemical Development: Used as an intermediate in the research and development of new, more selective pesticides and herbicides.

Basic Information

Product Name	3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,(3R)-(9Ci)
CAS No.	754170-16-6
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	(3R)-7-Amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 7-Amino-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, (3R)-; (R)-7-Amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 754170-16-6; (R)-7-Amino-Tic-OH; (3R)-7-Amino-Tic; 7-Amino-(R)-Tic
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity specifications suitable for research and development. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and related substance profiles are available upon request. Our quality system is designed to support cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.