Description

Methyl 4-Bromo-6-Carbamoylbenzo[B]Thiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates bromo, carbamoyl, and ester functional groups on a benzo[b]thiophene core, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Material Science: Serves as a building block for creating organic semiconductors, liquid crystals, and advanced polymers with specific electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic routes in heterocyclic chemistry.
• Custom Synthesis: A versatile starting material for the contract manufacturing of specialized, high-value fine chemicals and complex organic molecules.

Basic Information

Product Name	Methyl 4-Bromo-6-Carbamoylbenzo[B]Thiophene-2-Carboxylate
CAS No.	753455-44-6
Molecular Formula	C11H8BrNO3S
Molecular Weight	314.16 g/mol
Synonyms	Methyl 4-bromo-6-carbamoyl-1-benzothiophene-2-carboxylate; 4-Bromo-6-carbamoylbenzo[b]thiophene-2-carboxylic acid methyl ester; 2-Carbomethoxy-4-bromo-6-carbamoylbenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 4-bromo-6-carbamoyl-, methyl ester; 753455-44-6; Methyl 4-bromo-6-aminocarbonylbenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Bromo-6-Carbamoylbenzo[B]Thiophene-2-Carboxylate adheres to stringent in-process controls and final batch analysis to ensure consistent purity and identity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, impurity profile, and spectroscopic identification. We operate under a cGMP-compliant quality management system, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.