Description

6-tert-Butyl 2-Methyl 4-Bromobenzo[B]Thiophene-2,6-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated benzo[b]thiophene core. This compound is of significant value for its role as a versatile building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific receptors or enzymes.
• Organic Synthesis Building Block: Utilized in research-scale and process chemistry for constructing complex heterocyclic frameworks due to its reactive bromine and ester functional groups.
• Agrochemical Research: Employed in the development of new crop protection agents and herbicides, where the benzo[b]thiophene structure can impart unique biological activity.
• Material Science Precursor: Acts as a starting material for the synthesis of organic semiconductors or ligands for catalytic systems.
• Academic & R&D: Used in university and corporate laboratories for methodological studies in cross-coupling reactions, functional group transformations, and heterocyclic chemistry.

Basic Information

Product Name	6-tert-Butyl 2-Methyl 4-Bromobenzo[B]Thiophene-2,6-Dicarboxylate
CAS No.	753455-43-5
Molecular Formula	C₁₇H₁₉BrO₄S
Molecular Weight	399.30 g/mol
Synonyms	4-Bromo-6-(tert-butyl)-2-methylbenzo[b]thiophene-2,6-dicarboxylate; 6-tert-Butyl-2-methyl-4-bromobenzo[b]thiophene-2,6-dicarboxylic acid dimethyl ester; 4-Bromo-6-tert-butyl-2-methylbenzo[b]thiophene-2,6-dicarboxylate; Methyl 4-bromo-6-tert-butyl-2-methylbenzo[b]thiophene-2,6-dicarboxylate; Benzo[b]thiophene-2,6-dicarboxylic acid, 4-bromo-6-(1,1-dimethylethyl)-2-methyl-, 2,6-dimethyl ester; CAS 753455-43-5
EINECS	Contact for details

Quality Control

Our production of 6-tert-Butyl 2-Methyl 4-Bromobenzo[B]Thiophene-2,6-Dicarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.