Description

2-Amino-5-tert-Butyldimethylsilyloxy-Methyl-Thiazole is a high-value, organosilicon-protected thiazole derivative, serving as a critical synthetic intermediate. Its primary value lies in enabling advanced organic synthesis, particularly in the construction of complex heterocyclic molecules where selective protection and functional group manipulation are required. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with thiazole-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides requiring specific heterocyclic frameworks.
• Material Science Research: Serves as a precursor for functionalized molecules in advanced material applications.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecules, leveraging the TBDMS-protected hydroxyl group for selective reactions.
• Chemical Biology Probes: Useful in the development of molecular probes and labeled compounds for biological studies.

Basic Information

Product Name	2-Amino-5-tert-Butyldimethylsilyloxy-Methyl-Thiazole
CAS No.	752241-92-2
Molecular Formula	C11H22N2OSSi
Molecular Weight	258.46 g/mol
Synonyms	2-Amino-5-((tert-butyldimethylsilyloxy)methyl)thiazole; 5-((tert-Butyldimethylsilyloxy)methyl)-2-aminothiazole; 2-Amino-5-(tert-butyldimethylsiloxymethyl)thiazole; TBDMS-protected 2-Amino-5-hydroxymethylthiazole; 2-Amino-5-[(tert-butyldimethylsilyl)oxymethyl]thiazole; 2-Aminothiazole-5-methanol TBDMS ether; 752241-92-2
EINECS	Contact for details

Quality Control

Our 2-Amino-5-tert-Butyldimethylsilyloxy-Methyl-Thiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.