Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-3,6-Dihydroxy- is a high-purity, multifunctional chiral building block characterized by its unique norbornane skeleton. This compound is essential for advanced organic synthesis, offering a rigid, three-dimensional framework that is critical for modulating the stereochemistry and biological activity of target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), complex natural product analogs, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Asymmetric Catalysis: Used to construct sophisticated chiral ligands and organocatalysts for enantioselective synthesis.
• Agrochemical Research: Employed in the development of novel herbicides and pesticides with enhanced stereospecific activity.
• Material Science: Acts as a monomer or cross-linking agent for producing polymers with specific rigidity and thermal properties.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry and medicinal chemistry research programs.
• Peptidomimetics: Incorporated into peptide backbones to confer conformational restraint and improve metabolic stability.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-3,6-Dihydroxy-
CAS No.	752193-64-9
Molecular Formula	C8H11NO4
Molecular Weight	185.18 g/mol
Synonyms	2-Amino-3,6-dihydroxybicyclo[2.2.1]heptane-2-carboxylic acid; (1R,2S,4R)-2-Amino-3,6-dihydroxybicyclo[2.2.1]heptane-2-carboxylic acid; 2-Aminonorcamphor-3,6-diol-2-carboxylic acid; Amino-dihydroxy-norbornane-carboxylic acid; Bicyclo[2.2.1]heptane-2-carboxylic acid, 2-amino-3,6-dihydroxy-; 3,6-Dihydroxy-2-aminonorbornane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-3,6-Dihydroxy- adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.