Description

1-(5-Bromo-2-Chlorophenyl)Ethanol is a versatile chiral building block and key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of halogen substituents on the aromatic ring, which enable a range of subsequent coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated phenyl structure.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with specific optical or electronic properties.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and oxidation reactions.

Basic Information

Product Name	1-(5-Bromo-2-Chlorophenyl)Ethanol
CAS No.	749932-77-2
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	(5-Bromo-2-chlorophenyl)methanol; α-(5-Bromo-2-chlorophenyl)ethanol; 1-(5-Bromo-2-chlorophenyl)ethan-1-ol; (5-Bromo-2-chloro-phenyl)-methanol; 2-Chloro-5-bromobenzyl alcohol; 5-Bromo-2-chlorobenzyl alcohol; 1-(5-Bromo-2-chlorophenyl)methyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Chlorophenyl)Ethanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.