Description

Methyl 3-Amino-6-tert-Butyl-4,5,6,7-Tetrahydro-1-Benzothiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty fine chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new active ingredients in crop protection and pest management products.
• Organic Synthesis & Chemical Research: Used in academic and industrial R&D for constructing complex benzothiophene-based heterocycles and exploring new chemical reactions.
• Material Science Precursor: Potential application in the development of organic electronic materials and specialty polymers due to its fused ring system.
• Contract Manufacturing & Development (CDMO): Supplied to custom synthesis organizations for use in client-specific molecule production under cGMP or non-GMP conditions.

Basic Information

Item	Details
Product Name	Methyl 3-Amino-6-tert-Butyl-4,5,6,7-Tetrahydro-1-Benzothiophene-2-Carboxylate
CAS No.	749920-50-1
Molecular Formula	C14H21NO2S
Molecular Weight	267.39 g/mol
Synonyms	Methyl 3-amino-6-(tert-butyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylate; 6-tert-Butyl-3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylic acid methyl ester; 3-Amino-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylic acid methyl ester; 749920-50-1; Methyl 3-amino-6-tert-butyl-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-6-tert-Butyl-4,5,6,7-Tetrahydro-1-Benzothiophene-2-Carboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment supports compliance with relevant guidelines for intermediates used in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent oxidation and moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.