Description

5-(3,5-Dimethoxyphenyl)-1,3,4-Oxadiazole-2-Thiol is a specialized heterocyclic building block featuring a 1,3,4-oxadiazole core substituted with a thiol group and a dimethoxyphenyl moiety. This compound matters as a versatile intermediate for advanced organic synthesis, enabling the development of novel molecules with potential biological activity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the oxadiazole-thiol pharmacophore is relevant.
• Agrochemical Research: Used in developing new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, ligands for metal-organic frameworks (MOFs), or functional polymers.
• Chemical Biology Probe Development: Utilized in creating molecular probes or inhibitors to study biological pathways due to its potential metal-binding and reactive properties.
• Organic Synthesis Scaffold: Provides a rigid, aromatic heterocycle for medicinal chemistry programs aimed at structure-activity relationship (SAR) studies.
• Coordination Chemistry: The thiol group can act as a ligand for various metal ions, useful in catalysis or sensor development.

Basic Information

Product Name	5-(3,5-Dimethoxyphenyl)-1,3,4-Oxadiazole-2-Thiol
CAS No.	749902-08-7
Molecular Formula	C10H10N2O3S
Molecular Weight	238.26 g/mol
Synonyms	5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazole-2-thiol; 2-Mercapto-5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazole; 1,3,4-Oxadiazole-2-thiol, 5-(3,5-dimethoxyphenyl)-; 3,5-Dimethoxyphenyl-1,3,4-oxadiazole-2-thiol; 5-(3,5-Dimethoxy-phenyl)-[1,3,4]oxadiazole-2-thiol; 749902-08-7
EINECS	Contact for details

Quality Control

Our 5-(3,5-Dimethoxyphenyl)-1,3,4-Oxadiazole-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.