Description

1H-Indole-2,3-Dione, 5,7-Difluoro-6-Propyl- (9Ci) is a specialized fluorinated isatin derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is engineered for the development of novel compounds with targeted biological and material properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors seeking to innovate within fluorinated chemical spaces. The compound, identified by CAS number 749241-80-3, is supplied under stringent quality control to ensure reliability in critical R&D and production processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioactivity of the isatin core and the metabolic stability imparted by fluorine atoms.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the difluoro and propyl substituents can be leveraged to modulate activity, selectivity, and environmental persistence.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or emissive layer materials in OLED displays and lighting, where fluorinated compounds enhance device efficiency and stability.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysis, enabling more efficient and selective synthetic transformations in fine chemical production.
• Fluorescent Probe & Sensor Development: Utilized as a core structure for creating sensitive chemical probes and biosensors used in analytical chemistry and diagnostic applications.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in medicinal chemistry and heterocyclic chemistry.

Basic Information

Product Name	1H-Indole-2,3-Dione, 5,7-Difluoro-6-Propyl- (9Ci)
CAS No.	749241-80-3
Molecular Formula	C11H7F2NO2
Molecular Weight	223.18 g/mol
Synonyms	5,7-Difluoro-6-propylisatin; 6-Propyl-5,7-difluoro-1H-indole-2,3-dione; 5,7-Difluoro-6-propyl-1H-indole-2,3-dione; Isatin, 5,7-difluoro-6-propyl-; 749241-80-3; 5,7-Difluoro-6-n-propylisatin; 6-n-Propyl-5,7-difluoroindoline-2,3-dione
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-2,3-Dione, 5,7-Difluoro-6-Propyl- (9Ci) is produced and analyzed under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity building blocks for sensitive syntheses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.