Description

5-Fluoro-6-Methyl Isatin is a strategically important fluorinated isatin derivative, serving as a versatile and high-value building block in advanced organic synthesis. Its core value lies in enabling the development of novel compounds with enhanced biological activity and physicochemical properties. This intermediate is critically needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating next-generation active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers, dyes, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing activity-based probes and molecular tags to study enzyme function and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	5-Fluoro-6-Methyl Isatin
CAS No.	749240-54-8
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	5-Fluoro-6-methyl-1H-indole-2,3-dione; 6-Methyl-5-fluoroisatin; 1H-Indole-2,3-dione, 5-fluoro-6-methyl-; 5-Fluoro-6-methylindoline-2,3-dione
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methyl Isatin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support customer audits and can provide material to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.