Description

4,7-Difluoroisatin is a fluorinated derivative of isatin, a versatile heterocyclic building block. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isatin scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer components in electronic display technologies.
• Material Science Research: Employed in the creation of novel organic semiconductors, dyes, and photoactive materials.
• Chemical Biology Probes: Acts as a core structure for developing fluorescent tags or activity-based probes for studying biological processes.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	4,7-Difluoroisatin
CAS No.	749240-52-6
Molecular Formula	C8H3F2NO2
Molecular Weight	183.11 g/mol
Synonyms	4,7-Difluoro-1H-indole-2,3-dione; 4,7-Difluoro-2,3-dihydroindole-2,3-dione; 4,7-Difluoroindoline-2,3-dione; 1H-Indole-2,3-dione, 4,7-difluoro-; Isatin, 4,7-difluoro-; 4,7-Difluorooxindole; 4,7-Difluoro-2,3-dioxoindoline
EINECS	Contact for details

Quality Control

Our 4,7-Difluoroisatin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.