Description

Thiophene, 2-Ethyl-4-(4-Fluorophenyl)- (9Ci) is a specialized fluorinated thiophene derivative, a high-value building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate unique fluorinated heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the fluorinated thiophene core can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to the electron-rich thiophene ring.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical scaffold.

Basic Information

Product Name	Thiophene, 2-Ethyl-4-(4-Fluorophenyl)- (9Ci)
CAS No.	748817-89-2
Molecular Formula	C12H11FS
Molecular Weight	206.28 g/mol
Synonyms	2-Ethyl-4-(4-fluorophenyl)thiophene; 4-(4-Fluorophenyl)-2-ethylthiophene; 2-Ethyl-4-(p-fluorophenyl)thiophene; 748817-89-2; Thiophene, 2-ethyl-4-(4-fluorophenyl)-; 4-(4-Fluorophenyl)-2-ethyl-thiophene
EINECS	Contact for details

Quality Control

Our Thiophene, 2-Ethyl-4-(4-Fluorophenyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material that meets the stringent requirements for pharmaceutical R&D and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.