Description

2-Thiophenecarboxylicacid,3-Amino-5-(1,1-Dimethylethyl)-(9Ci) is a specialized heterocyclic building block featuring a thiophene core substituted with amino and tert-butyl groups. This compound matters as a high-value intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors where its unique structure enables the development of novel active ingredients. It is primarily needed by R&D chemists and process development scientists working on advanced organic synthesis, medicinal chemistry, and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the thiophene moiety can contribute to biological activity.
• Material Science Research: Acts as a precursor for functionalized polymers and organic electronic materials due to its conjugated thiophene system.
• Ligand and Catalyst Development: The amino group allows for chelation, making it useful in designing novel ligands for catalytic processes.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or probes for studying biological mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-purity heterocyclic frameworks.

Basic Information

Product Name	2-Thiophenecarboxylicacid,3-Amino-5-(1,1-Dimethylethyl)-(9Ci)
CAS No.	746671-67-0
Molecular Formula	C9H13NO2S
Molecular Weight	199.27 g/mol
Synonyms	3-Amino-5-tert-butylthiophene-2-carboxylic acid; 5-tert-Butyl-3-aminothiophene-2-carboxylic acid; 3-Amino-5-(1,1-dimethylethyl)-2-thiophenecarboxylic acid; 3-Amino-5-(tert-butyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-amino-5-(1,1-dimethylethyl)- (9CI); 746671-67-0; 3-Amino-5-tert-butyl-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylicacid,3-Amino-5-(1,1-Dimethylethyl)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.