Description

4-Bromo-1-Methoxyisoquinoline is a versatile halogenated isoquinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure makes it a valuable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and methoxy functionalities into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other electronic materials due to its fused aromatic system.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create more complex, functionalized isoquinoline derivatives.
• Ligand & Catalyst Development: Utilized in the preparation of nitrogen-containing ligands for metal catalysis.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	4-Bromo-1-Methoxyisoquinoline
CAS No.	746668-73-5
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	1-Methoxy-4-bromoisoquinoline; 4-Bromo-1-methoxy-isoquinoline; Isoquinoline, 4-bromo-1-methoxy-; 746668-73-5; 4-Bromo-1-isoquinolinyl methyl ether; 4-Bromo-1-methoxyisoquinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.