Description

3-Thiophenecarboxylicacid,4-Aminotetrahydro-,Ethylester,1-Oxide,(3Alpha,4Alpha)- CAS NO 746577-31-1 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functionalized thiophene scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging the thiophene moiety for biological activity.
• Organic Synthesis & Catalysis: Serves as a versatile precursor in academic and industrial organic chemistry for constructing complex heterocyclic compounds.
• Material Science Research: Investigated for potential applications in organic electronics and functional materials due to its conjugated system.

Basic Information

Product Name	3-Thiophenecarboxylicacid,4-Aminotetrahydro-,Ethylester,1-Oxide,(3Alpha,4Alpha)-
CAS No.	746577-31-1
Molecular Formula	C8H13NO3S
Molecular Weight	203.26 g/mol
Synonyms	(3α,4α)-4-Aminotetrahydro-3-thiophenecarboxylic acid ethyl ester 1-oxide; Ethyl (3α,4α)-4-amino-1-oxido-2,5-dihydro-3-thiophenecarboxylate; 4-Aminotetrahydrothiophene-3-carboxylic acid ethyl ester 1-oxide; 746577-31-1; (3R,4R)-4-Amino-1-oxido-2,5-dihydrothiophene-3-carboxylic acid ethyl ester; (3Alpha,4Alpha)-4-Aminotetrahydro-3-thiophenecarboxylic acid ethyl ester 1-oxide; Tetrahydro-4-amino-3-thiophenecarboxylic acid ethyl ester S-oxide
EINECS	Contact for details

Quality Control

Our production of 3-Thiophenecarboxylicacid,4-Aminotetrahydro-,Ethylester,1-Oxide,(3Alpha,4Alpha)- adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure identity, potency, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications and supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.