Description

Bicyclo[2.2.1]Heptan-2-Amine, 7,7-Dimethyl-1-[(Methylthio)Methyl]-, (1S,2R,4R)- (9Ci) is a high-purity, stereochemically defined chiral amine building block of significant interest in advanced organic synthesis. Its unique bicyclic framework, functionalized with both an amine and a methylthioether group, makes it a valuable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, chiral catalyst development, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand: Serves as a precursor for sophisticated chiral ligands used in transition metal catalysis to induce high enantioselectivity in synthetic reactions.
• Agrochemical Synthesis: Used in the development of new, stereospecific herbicides, fungicides, and insecticides where the specific 3D structure is critical for bioactivity.
• Advanced Material Research: Employed in academic and industrial R&D for creating chiral polymers, liquid crystals, or other functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Acts as a building block for synthesizing molecular probes to study enzyme mechanisms or receptor interactions in biochemical systems.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptan-2-Amine, 7,7-Dimethyl-1-[(Methylthio)Methyl]-, (1S,2R,4R)- (9Ci)
CAS No.	745801-35-8
Molecular Formula	C11H21NS
Molecular Weight	199.36 g/mol
Synonyms	(1S,2R,4R)-7,7-Dimethyl-1-[(methylthio)methyl]bicyclo[2.2.1]heptan-2-amine; (1S,2R,4R)-1-[(Methylsulfanyl)methyl]-7,7-dimethylbicyclo[2.2.1]heptan-2-amine; endo-7,7-Dimethyl-1-[(methylthio)methyl]bicyclo[2.2.1]heptan-2-amine (specific isomer); Chiral Norbornane-based amine; 2-Aminonorbornane derivative; Bicyclo[2.2.1]heptane-2-methanamine, 7,7-dimethyl-1-[(methylthio)methyl]-, (1S,2R,4R)-
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Certificates of Analysis (COA) are provided with each shipment, detailing critical parameters such as chiral purity (by chiral HPLC or GC), chemical purity, and identity confirmation. We support development and scale-up projects with custom synthesis and purification services to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.