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2-Bromoquinoline-3-Boronic Acid CAS NO 745784-05-8


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CAS No.:745784-05-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromoquinoline-3-Boronic Acid is a versatile and high-value organoboron building block, essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex quinoline-based molecular architectures.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
  • Agrochemical Synthesis: Used in the development of advanced fungicides, herbicides, and insecticides with quinoline scaffolds.
  • Material Science: Serves as a precursor for creating organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional materials.
  • Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and enzyme inhibitors for target identification and validation.
  • Catalyst & Ligand Development: Useful for constructing novel nitrogen-containing ligands for transition metal catalysis.
  • Academic & Contract Research: Fundamental reagent for methodological development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name 2-Bromoquinoline-3-Boronic Acid
CAS No. 745784-05-8
Molecular Formula C9H7BBrNO2
Molecular Weight 251.88 g/mol
Synonyms (2-Bromoquinolin-3-yl)boronic acid; 3-Borono-2-bromoquinoline; 2-Bromo-3-quinolineboronic acid; Quinoline, 2-bromo-3-borono-; 2-Bromoquinoline-3-boronic acid pinacol ester (common derivative); B-(2-Bromoquinolin-3-yl)boronic acid; 745784-05-8 (CAS); 2-Br-3-B(OH)2-Quinoline
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Quality Control

Our 2-Bromoquinoline-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee reliable and reproducible performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥95% (Typical 97-99%)
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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