Description

n-(5-Bromo-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide is a high-purity, specialized organic intermediate featuring a brominated thiazole core and a trifluoroacetamide functional group. This compound is critical for research and development in advanced chemical synthesis, offering a versatile building block for creating novel molecular architectures. It is primarily sought by pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science: Acts as a building block for advanced polymers or liquid crystals, where the bromine atom allows for further functionalization.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex heterocyclic systems into target molecules.
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery research in university and CRO laboratories.

Basic Information

Product Name	n-(5-Bromo-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide
CAS No.	745053-65-0
Molecular Formula	C5H2BrF3N2OS
Molecular Weight	274.04 g/mol
Synonyms	2,2,2-Trifluoro-N-(5-bromo-1,3-thiazol-2-yl)acetamide; 5-Bromo-2-(2,2,2-trifluoroacetamido)thiazole; N-(5-Bromothiazol-2-yl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoroacetamide, N-(5-bromo-2-thiazolyl)-; 745053-65-0; 5-Bromo-2-trifluoroacetylamino-thiazole; 2-Acetamide, N-(5-bromo-2-thiazolyl)-2,2,2-trifluoro-
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.