Description

5-Fluorothiazol-2-Amine Hydrochloride is a high-purity organic salt building block essential for advanced pharmaceutical and agrochemical research. This compound serves as a critical precursor in the synthesis of novel heterocyclic molecules, enabling the development of targeted bioactive agents. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and anti-infective research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the fluorinated thiazole moiety for enhanced biological activity.
• Chemical Biology Research: Employed as a probe or building block in the study of enzyme mechanisms and biological pathways.
• Material Science: Serves as a precursor for functionalized polymers or organic electronic materials requiring specific heterocyclic architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and active pharmaceutical ingredients (APIs) on a commercial scale.

Basic Information

Product Name	5-Fluorothiazol-2-Amine Hydrochloride
CAS No.	745053-64-9
Molecular Formula	C3H4FN2S·HCl
Molecular Weight	154.60 g/mol (Free base: 118.14 g/mol)
Synonyms	2-Amino-5-fluorothiazole Hydrochloride; 5-Fluoro-1,3-thiazol-2-amine hydrochloride; 5-Fluoro-2-thiazolamine hydrochloride; 5-Fluoro-2-aminothiazole HCl; 5-Fluoro-thiazol-2-ylamine hydrochloride; 2-Thiazolamine, 5-fluoro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 5-Fluorothiazol-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.