Description

6-Isoquinolinamine,Decahydro-2-Methyl-,(4Aalpha,6Beta,8Aalpha)-(9Ci) is a high-purity, stereochemically defined decahydroisoquinoline derivative, a key structural motif in medicinal chemistry. This compound matters as a sophisticated chiral building block for the research and development of novel pharmaceutical agents, particularly in central nervous system (CNS) and other therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing complex molecules and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral scaffold for the synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its rigid, three-dimensional structure.
• Asymmetric Synthesis: Serves as a starting material or intermediate in the preparation of enantiomerically pure compounds for biological testing.
• Chemical Reference Standard: Employed as an analytical standard for method development and quality control in API manufacturing.
• Library Synthesis: Utilized in combinatorial chemistry to create diverse compound libraries for high-throughput screening.
• Academic Research: Used in universities and research institutes for studying alkaloid chemistry, heterocyclic compound reactivity, and novel synthetic methodologies.

Basic Information

Product Name	6-Isoquinolinamine,Decahydro-2-Methyl-,(4Aalpha,6Beta,8Aalpha)-(9Ci)
CAS No.	744994-89-6
Molecular Formula	C10H20N2
Molecular Weight	168.28 g/mol
Synonyms	Decahydro-2-methyl-6-isoquinolinamine (4aα,6β,8aα)-; (4aR,6S,8aS)-Decahydro-2-methyl-6-isoquinolinamine; (4aα,6β,8aα)-Decahydro-2-methyl-6-isoquinolinamine; 2-Methyldecahydro-6-isoquinolinamine; 6-Amino-2-methyldecahydroisoquinoline; (4aR,6S,8aS)-2-Methyl-decahydro-isoquinolin-6-ylamine; A key intermediate for pharmaceutical research.
EINECS	Contact for details

Quality Control

Our 6-Isoquinolinamine,Decahydro-2-Methyl-,(4Aalpha,6Beta,8Aalpha)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.