Description

Thieno[3,2-C]Pyridine-5(4H)-Acetic Acid, A-(2-Chlorophenyl)-6,7-Dihydro-, Methyl Ester, (As)-, Benzenesulfonate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the research and development of new drug candidates, particularly those targeting the central nervous system or other specialized therapeutic areas.
• Medicinal Chemistry Research: Used by R&D scientists for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs) during clinical development phases.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Fine Chemical Production: Utilized by contract development and manufacturing organizations (CDMOs) for the custom synthesis of complex molecules for clients.

Basic Information

Item	Detail
Product Name	Thieno[3,2-C]Pyridine-5(4H)-Acetic Acid, A-(2-Chlorophenyl)-6,7-Dihydro-, Methyl Ester, (As)-, Benzenesulfonate
CAS No.	744256-69-7
Molecular Formula	C22H20ClNO4S2
Molecular Weight	469.98 g/mol
Synonyms	(aS)-α-(2-Chlorophenyl)-4,5-dihydro-6,7-dihydrothieno[3,2-c]pyridine-5-acetic acid methyl ester benzenesulfonate; Methyl (αS)-α-(2-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-acetate benzenesulfonate; Prasugrel related compound (benzenesulfonate salt); Prasugrel benzenesulfonate intermediate; Thienopyridine derivative benzenesulfonate salt.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability for critical R&D and scale-up work. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.