Description

3(5H)-Indolizinone,6,7-Dihydro-6,7-Dihydroxy-,(6S,7S)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in the precise (6S,7S)-dihydroxyindolizinone scaffold, which serves as a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality can influence biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Advanced Material Precursor: Potential building block for specialty polymers or organic electronic materials requiring specific functional group arrays.
• Academic & Institutional Research: Employed in university and R&D institute laboratories for fundamental studies in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	3(5H)-Indolizinone,6,7-Dihydro-6,7-Dihydroxy-,(6S,7S)-(9Ci)
CAS No.	744200-08-6
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	(6S,7S)-6,7-Dihydroxy-6,7-dihydro-3(5H)-indolizinone; (6S,7S)-6,7-Dihydroxy-5,6,7,8-tetrahydroindolizin-3-one; (6S,7S)-Dihydroxyindolizinone; (6S,7S)-Tetrahydroindolizine-3,6,7-trione derivative; Chiral dihydroxyindolizinone; (S,S)-Dihydroxy-tetrahydroindolizinone; 744200-08-6; (9CI) numbered indolizinone derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral chromatography, NMR, and mass spectrometry to confirm identity, stereochemical purity (enantiomeric excess), and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.