Description

2-Azabicyclo[3.1.0]Hexane-2-Ethanol,(1R,5S)-(9Ci) is a high-purity chiral bicyclic amine derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate). This compound matters for its role in constructing complex molecular architectures with precise stereochemistry, enabling the synthesis of novel active pharmaceutical ingredients. Pharmaceutical R&D and fine chemical synthesis teams need it to develop next-generation therapeutics, particularly in areas like central nervous system (CNS) agents and antiviral drugs.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex drug candidates, especially in neurological and antiviral research.
• Asymmetric Synthesis: Used as a ligand or precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• Fine Chemical Production: Integral component in the multi-step synthesis of specialty chemicals requiring rigid, three-dimensional scaffolds.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development in organic and synthetic chemistry laboratories.

Basic Information

Product Name	2-Azabicyclo[3.1.0]Hexane-2-Ethanol,(1R,5S)-(9Ci)
CAS No.	743438-28-0
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(1R,5S)-2-(2-Hydroxyethyl)-2-azabicyclo[3.1.0]hexane; (1R,5S)-2-Azabicyclo[3.1.0]hexane-2-ethanol; 2-(2-Azabicyclo[3.1.0]hex-2-yl)ethanol, (1R,5S)-rel-; 743438-28-0; Bicyclic amine ethanol derivative; Chiral azabicyclohexane ethanol
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[3.1.0]Hexane-2-Ethanol,(1R,5S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, supporting compliance with cGMP and ICH Q7 guidelines for API intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.