Description

3-(Methylthio)Azetidine is a versatile, high-purity heterocyclic building block containing both an azetidine ring and a methylthio functional group. This unique structure makes it a critical intermediate for the synthesis of novel pharmaceuticals and advanced agrochemicals, enabling the introduction of constrained ring systems and sulfur-based pharmacophores. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the sulfur moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers with specific thermal or chemical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	3-(Methylthio)Azetidine
CAS No.	742670-23-1
Molecular Formula	C4H9NS
Molecular Weight	103.18 g/mol
Synonyms	3-(Methylsulfanyl)azetidine; 3-(Methylthio)azetidine; Azetidine, 3-(methylthio)-; 3-Methylsulfanyl-azetidine; 3-Methylthioazetidine; 3-(Methylmercapto)azetidine; 3-(Thiomethyl)azetidine; 742670-23-1 (CAS)
EINECS	Contact for details

Quality Control

Our 3-(Methylthio)Azetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen) to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.