Description

(2Z)-2-(Aminomethyl)-3-(1-Benzyl-1H-Indol-3-Yl)Prop-2-En-1-Ol CAS NO 742651-29-2 is a high-purity, non-natural amino acid derivative featuring a benzyl-protected indole moiety. This compound serves as a critical chiral building block and advanced intermediate in modern synthetic organic chemistry. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing novel active pharmaceutical ingredients (APIs) and complex molecular entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting neurological and oncological pathways.
• Peptidomimetic Research: Used to incorporate constrained, non-proteinogenic amino acid structures into peptide analogs to enhance stability and bioavailability.
• Chemical Biology Probe Development: Serves as a scaffold for creating fluorescent or affinity tags to study protein-ligand interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective catalytic reactions.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Academic Research: Fundamental building block for investigating new organic reaction methodologies and heterocyclic chemistry.

Basic Information

Product Name	(2Z)-2-(Aminomethyl)-3-(1-Benzyl-1H-Indol-3-Yl)Prop-2-En-1-Ol
CAS No.	742651-29-2
Molecular Formula	C20H20N2O
Molecular Weight	304.39 g/mol
Synonyms	2-(Aminomethyl)-3-(1-benzyl-1H-indol-3-yl)prop-2-en-1-ol; (Z)-2-(Aminomethyl)-3-(1-benzylindol-3-yl)prop-2-en-1-ol; 1H-Indole-3-propanol, α-(aminomethyl)-1-benzyl-, (αZ)-; 742651-29-2; 1-Benzyl-3-[(1Z)-3-hydroxy-2-(hydroxymethyl)prop-1-en-1-yl]-1H-indole; (2Z)-2-(Aminomethyl)-3-(1-benzylindol-3-yl)prop-2-en-1-ol; (Z)-2-(Aminomethyl)-3-(1-benzyl-1H-indol-3-yl)-2-propen-1-ol
EINECS	Contact for details

Quality Control

Our production of (2Z)-2-(Aminomethyl)-3-(1-Benzyl-1H-Indol-3-Yl)Prop-2-En-1-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent screening. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.