Description

1''-Methyl-5-Methoxyspiro[Indole-3,4''-Piperidine]2(1H)One is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic indole-piperidine structure. This compound is of significant value for its role as a key building block in the synthesis of novel therapeutic agents, particularly within central nervous system (CNS) research. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially those targeting neurological pathways and receptor modulation.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS-Active Compound Development: Used in the research and development of molecules targeting serotonin, dopamine, or other neurotransmitter receptors.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value organic compounds.
• Biochemical Tool Compound: May be utilized in vitro to study biological mechanisms and pathways related to its structural class.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1''-Methyl-5-Methoxyspiro[Indole-3,4''-Piperidine]2(1H)One
CAS No.	742067-27-2
Molecular Formula	C15H18N2O2
Molecular Weight	258.32 g/mol
Synonyms	1'-Methyl-5-methoxyspiro[indole-3,4'-piperidin]-2(1H)-one; 5-Methoxy-1'-methylspiro[1,3-dihydro-2H-indole-3,4'-piperidin]-2-one; 742067-27-2; Spiro[indole-3,4'-piperidine] derivative; 1'-Methyl-5-methoxyspiro[indoline-3,4'-piperidin]-2-one
EINECS	Contact for details

Quality Control

Our 1''-Methyl-5-Methoxyspiro[Indole-3,4''-Piperidine]2(1H)One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.