Description

(R)-4-[4-(Oxiranylmethoxy)-1,2,5-Thiadiazol-3-Yl]Morpholine is a high-purity chiral building block featuring a unique heterocyclic structure combining morpholine, thiadiazole, and an oxirane (epoxide) moiety. This compound matters as a critical intermediate for the synthesis of advanced pharmaceutical agents, particularly in the development of targeted kinase inhibitors and other bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Process Chemistry: Serves as a building block in the scalable synthesis of complex active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized for introducing chirality and specific heterocyclic frameworks into target molecules.
• Bioconjugation & Probe Development: The reactive epoxide group can be used for selective labeling and conjugation in chemical biology.
• Agrochemical Research: Potential intermediate in the discovery of new crop protection agents with specific modes of action.

Basic Information

Product Name	(R)-4-[4-(Oxiranylmethoxy)-1,2,5-Thiadiazol-3-Yl]Morpholine
CAS No.	741719-53-9
Molecular Formula	C9H13N3O3S
Molecular Weight	243.28 g/mol
Synonyms	(R)-4-(4-(Oxiran-2-ylmethoxy)-1,2,5-thiadiazol-3-yl)morpholine; (R)-4-(4-(Oxiranylmethoxy)-1,2,5-thiadiazol-3-yl)morpholine; (R)-4-(4-(Glycidyloxy)-1,2,5-thiadiazol-3-yl)morpholine; (R)-3-Morpholino-1,2,5-thiadiazol-4-yl glycidyl ether; (R)-4-(4-((Oxiran-2-yl)methoxy)-1,2,5-thiadiazol-3-yl)morpholine; 741719-53-9; (R)-enantiomer of 4-[4-(Oxiranylmethoxy)-1,2,5-thiadiazol-3-yl]morpholine
EINECS	Contact for details

Quality Control

Our (R)-4-[4-(Oxiranylmethoxy)-1,2,5-Thiadiazol-3-Yl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.