Description

1H-Benz[E]Isoindole,6-Ethoxy-2,3,3A,4,5,9B-Hexahydro-,(3Ar,9Br)-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined polycyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and specialty organic materials. The compound, CAS number 741653-69-0, is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive synthetic applications.

Application

This specialized intermediate serves as a key precursor in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific stereochemical activity.
• Material Science: Serves as a monomer or precursor for creating specialized polymers and organic electronic materials.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in synthetic organic chemistry and catalysis.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of fine chemicals.

Basic Information

Product Name	1H-Benz[E]Isoindole,6-Ethoxy-2,3,3A,4,5,9B-Hexahydro-,(3Ar,9Br)-(9Ci)
CAS No.	741653-69-0
Molecular Formula	C14H19NO
Molecular Weight	217.31 g/mol
Synonyms	(3aR,9bR)-6-Ethoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindole; 6-Ethoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindole, (3aR,9bR)-; 1H-Benz[e]isoindole, 6-ethoxy-2,3,3a,4,5,9b-hexahydro-, (3aR,9bR)-; (3aR,9bR)-6-Ethoxy-1,2,3,3a,4,5-hexahydro-9bH-benz[e]isoindole; Hexahydrobenz[e]isoindole derivative; Stereoisomeric benzisoindole intermediate.
EINECS	Contact for details

Quality Control

Our production of 1H-Benz[E]Isoindole,6-Ethoxy-2,3,3A,4,5,9B-Hexahydro-,(3Ar,9Br)-(9Ci) adheres to a rigorous quality management system. Each batch is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the exacting standards required for pharmaceutical R&D and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed to prevent moisture absorption and potential contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.