Description

1H-Indol-3-Ylboronic Acid is a versatile and high-value boronic acid derivative, essential for modern synthetic organic chemistry. Its primary value lies in its role as a key building block in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex indole-containing molecules. This compound is critically needed by research institutions and pharmaceutical companies engaged in drug discovery, agrochemical development, and the synthesis of advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the biologically important indole scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific indole-based structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysts, and advanced polymers.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry for creating novel carbon-carbon bonds via palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes used to study biological pathways and protein functions.

Basic Information

Item	Details
Product Name	1H-Indol-3-Ylboronic Acid
CAS No.	741253-05-4
Molecular Formula	C8H8BNO2
Molecular Weight	160.97 g/mol
Synonyms	3-Indoleboronic Acid; 1H-Indole-3-boronic Acid; Indol-3-ylboronic Acid; (1H-Indol-3-yl)boronic Acid; 3-Boron-1H-indole; B-(1H-Indol-3-yl)boronic Acid; 741253-05-4; 3-Indolylboronic Acid
EINECS	Contact for details

Quality Control

Our 1H-Indol-3-Ylboronic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical: 98-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.