Description

6H-Pyrrolo[4,3,2-Ef][2,3]Benzodiazepin-6-One,8-Amino-2-Ethyl-1,5-Dihydro-(9Ci) is a high-purity, complex heterocyclic organic compound belonging to the benzodiazepine class. This specialized chemical serves as a critical advanced intermediate in modern pharmaceutical research and development, enabling the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for central nervous system (CNS) drug discovery.
• Preclinical Development: Serves as a precursor for producing compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and receptor interactions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	6H-Pyrrolo[4,3,2-Ef][2,3]Benzodiazepin-6-One,8-Amino-2-Ethyl-1,5-Dihydro-(9Ci)
CAS No.	740083-25-4
Molecular Formula	C13H14N4O
Molecular Weight	242.28 g/mol
Synonyms	8-Amino-2-ethyl-1,5-dihydro-6H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-6-one; 8-Amino-2-ethyl-1,5-dihydropyrrolo[4,3,2-ef][2,3]benzodiazepin-6-one; 740083-25-4; 2-Ethyl-8-amino-1,5-dihydro-6H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-6-one; Pyrrolobenzodiazepine derivative; PBD intermediate; Aminoethyl dihydropyrrolobenzodiazepinone
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request. We support development under GMP-like conditions for research use, with scalability for preclinical needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.