Description

3-Amino-1-(5,6-Dichloroisoindolin-2-Yl)-3-Methylbutan-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoindolinone core structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel small-molecule drugs.
• Oncology Research: Used in the synthesis of potential anti-cancer compounds targeting specific biological pathways.
• CNS Drug Discovery: Serves as a building block for candidates aimed at neurological and psychiatric disorders.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production of new chemical entities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development programs.
• Academic & Institutional Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Amino-1-(5,6-Dichloroisoindolin-2-Yl)-3-Methylbutan-1-One
CAS No.	739365-47-0
Molecular Formula	C13H14Cl2N2O
Molecular Weight	285.17 g/mol
Synonyms	3-Amino-1-(5,6-dichloro-2,3-dihydro-1H-isoindol-2-yl)-3-methylbutan-1-one; 3-Amino-3-methyl-1-(5,6-dichloroisoindolin-2-yl)butan-1-one; 1-(5,6-Dichloro-1,3-dihydro-2H-isoindol-2-yl)-3-amino-3-methyl-1-butanone; 739365-47-0; 5,6-Dichloro-2-(3-amino-3-methyl-1-oxobutyl)isoindoline
EINECS	Contact for details

Quality Control

Our 3-Amino-1-(5,6-Dichloroisoindolin-2-Yl)-3-Methylbutan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.