Description

3-Amino-1-(4,7-Dichloroisoindolin-2-Yl)-3-Methylbutan-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoindolinone core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates, especially in oncology and central nervous system (CNS) research.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new chemical entities.
• Pre-clinical Development: Serves as a critical material for producing batches of experimental compounds for pharmacological and toxicological studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	3-Amino-1-(4,7-Dichloroisoindolin-2-Yl)-3-Methylbutan-1-One
CAS No.	739365-42-5
Molecular Formula	C13H14Cl2N2O
Molecular Weight	285.17 g/mol
Synonyms	3-Amino-1-(4,7-dichloro-2,3-dihydro-1H-isoindol-2-yl)-3-methylbutan-1-one; 3-Amino-3-methyl-1-(4,7-dichloro-1,3-dihydro-2H-isoindol-2-yl)butan-1-one; 739365-42-5; 4,7-Dichloro-2-(3-amino-3-methyl-1-oxobutyl)isoindoline
EINECS	Contact for details

Quality Control

Our production of 3-Amino-1-(4,7-Dichloroisoindolin-2-Yl)-3-Methylbutan-1-One adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and rigorous control of residual solvents and impurities. Certificates of Analysis (COA) with full traceability are provided to ensure compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.