Description

3-Amino-1-(5-Chloroisoindolin-2-Yl)-3-Methylbutan-1-One is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring isoindoline-based scaffolds. It is primarily needed by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemists exploring new chemical entities and structure-activity relationships (SAR).
• Custom Synthesis: Used in contract manufacturing organizations (CMOs) for the production of specialized, non-commercial compounds for clinical trials.
• API Manufacturing: Incorporated into the multi-step synthesis of complex final active pharmaceutical ingredients requiring the 5-chloroisoindolin moiety.

Basic Information

Product Name	3-Amino-1-(5-Chloroisoindolin-2-Yl)-3-Methylbutan-1-One
CAS No.	739365-38-9
Molecular Formula	C13H15ClN2O
Molecular Weight	250.72 g/mol
Synonyms	3-Amino-1-(5-chloro-2,3-dihydro-1H-isoindol-2-yl)-3-methylbutan-1-one; 3-Methyl-3-amino-1-(5-chloroisoindolin-2-yl)butan-1-one; 739365-38-9; 5-Chloro-2-(3-amino-3-methyl-1-oxobutyl)isoindoline; 1-(5-Chloro-1,3-dihydro-2H-isoindol-2-yl)-3-amino-3-methyl-1-butanone
EINECS	Contact for details

Quality Control

Our 3-Amino-1-(5-Chloroisoindolin-2-Yl)-3-Methylbutan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.