Description

1-(Hydroxymethyl)-1H-Indole-5-Carboxylic Acid is a versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a carboxylic acid and a hydroxymethyl group on the indole scaffold, makes it a valuable intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced organic materials.
• Bioconjugation & Probe Development: Utilized in the design of fluorescent probes, biomarkers, and other biochemical tools due to its reactive sites.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory chemistry projects.

Basic Information

Product Name	1-(Hydroxymethyl)-1H-Indole-5-Carboxylic Acid
CAS No.	739365-16-3
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	5-Carboxy-1H-indole-1-methanol; 1H-Indole-5-carboxylic acid, 1-(hydroxymethyl)-; 1-(Hydroxymethyl)indole-5-carboxylic acid; 5-Carboxyindole-1-methanol; 1H-Indole-1-methanol, 5-carboxy-; 739365-16-3
EINECS	Contact for details

Quality Control

Our production of 1-(Hydroxymethyl)-1H-Indole-5-Carboxylic Acid adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. Our products are manufactured in facilities that follow cGMP principles where applicable. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.