Description

2H-Pyrrol-5-Amine,3,4-Dihydro-2-(Methoxymethyl)-,(S)-(9Ci) is a chiral, non-racemic pyrrolidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-value pharmaceutical intermediate and chiral building block for constructing complex molecules with defined stereochemistry. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Serves as a crucial building block for constructing complex, enantiomerically pure molecules in medicinal chemistry and process development.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and pesticides requiring specific stereochemical configurations for optimal activity.
• Ligand and Catalyst Development: Acts as a precursor for novel chiral ligands and organocatalysts used in stereoselective transformations.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	2H-Pyrrol-5-Amine,3,4-Dihydro-2-(Methoxymethyl)-,(S)-(9Ci)
CAS No.	739344-59-3
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(S)-3,4-Dihydro-2-(methoxymethyl)-2H-pyrrol-5-amine; (S)-2-(Methoxymethyl)-2,3-dihydro-1H-pyrrol-5-amine; (5S)-2-(Methoxymethyl)-2,3-dihydro-1H-pyrrol-5-amine; 739344-59-3; (S)-2-(Methoxymethyl)-4,5-dihydro-3H-pyrrol-5-amine; (S)-5-Amino-2-(methoxymethyl)-2,3-dihydro-1H-pyrrole; Chiral Pyrrolidine Amine Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to guarantee high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.