Description

1-Azabicyclo[2.2.2]Octane,3-(Aminooxy)-,(S)-(9Ci) is a chiral bicyclic amine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where its unique stereochemistry and functional groups enable precise chemical transformations.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Ligand Precursor: Used in the development of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.
• Agrochemical Research: Employed in the research and development of new, more effective crop protection agents with specific stereochemical requirements.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, enabling new routes to complex nitrogen-containing heterocycles.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octane,3-(Aminooxy)-,(S)-(9Ci)
CAS No.	739343-64-7
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(S)-3-(Aminooxy)quinuclidine; (S)-Quinuclidin-3-yloxyamine; (S)-3-Aminoxyquinuclidine; (S)-1-Azabicyclo[2.2.2]octan-3-yloxyamine; 3-(Aminooxy)-(S)-1-azabicyclo[2.2.2]octane; (S)-3-Oxyaminoquinuclidine; (S)-3-Hydroxyaminoquinuclidine; (S)-3-(Hydroxyamino)quinuclidine
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]Octane,3-(Aminooxy)-,(S)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.