Description

1-Azabicyclo[2.2.2]Octane,3-(Aminooxy)-,(R)-(9Ci) is a high-value, chiral bicyclic amine derivative of quinuclidine, serving as a sophisticated building block in advanced organic synthesis. Its unique structure, featuring a reactive aminooxy group on the (R)-configured quinuclidine scaffold, makes it a critical intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs), chiral catalysts, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand: Used to develop and synthesize chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study enzyme mechanisms and protein interactions via oxime ligation.
• Agrochemical Synthesis: Intermediate in the production of advanced, stereospecific pesticides and herbicides.
• Material Science Research: Precursor for functionalized polymers and advanced organic materials requiring specific stereochemical orientation.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octane,3-(Aminooxy)-,(R)-(9Ci)
CAS No.	738558-73-1
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(R)-3-(Aminooxy)quinuclidine; (R)-Quinuclidin-3-yloxyamine; (3R)-1-Azabicyclo[2.2.2]octan-3-yloxyamine; (R)-3-Aminoxyquinuclidine; 3-(Aminooxy)-(R)-quinuclidine; (R)-3-Oxyaminoquinuclidine; 1-Azabicyclo[2.2.2]octan-3-ol, O-amino-, (3R)-; Aminooxy-(R)-quinuclidine
EINECS	Contact for details

Quality Control

Our production of 1-Azabicyclo[2.2.2]Octane,3-(Aminooxy)-,(R)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques, including chiral HPLC, to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing specific results is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.