Description

2-(2-Chloro-Acetylamino)-4-(5-Methyl-Furan-2-Yl)-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining furan and thiophene rings. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Serves as a building block in the development of complex Active Pharmaceutical Ingredients (APIs), especially those containing fused heterocyclic systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Chemical Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-4-(5-Methyl-Furan-2-Yl)-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	736960-88-6
Molecular Formula	C15H14ClNO4S
Molecular Weight	339.79 g/mol
Synonyms	Ethyl 2-[(2-chloroacetyl)amino]-4-(5-methyl-2-furanyl)-3-thiophenecarboxylate; 2-[(2-Chloroacetyl)amino]-4-(5-methyl-2-furanyl)thiophene-3-carboxylic Acid Ethyl Ester; 2-(2-Chloroacetamido)-4-(5-methylfuran-2-yl)thiophene-3-carboxylic acid ethyl ester; CAS 736960-88-6; 4-(5-Methylfuran-2-yl)-2-(2-chloroacetamido)thiophene-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Acetylamino)-4-(5-Methyl-Furan-2-Yl)-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We support development projects with custom purity grades and can provide materials suitable for preclinical and clinical stage applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.