Description

(R)-4-(Indol-3-Yl)-β-Homoalanine is a chiral, non-proteinogenic amino acid derivative featuring an indole moiety. This compound matters as a sophisticated building block in advanced pharmaceutical research and development, enabling the synthesis of novel bioactive molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and biotechnology industries for applications in medicinal chemistry, peptide mimetics, and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in oncology and CNS disorders.
• Peptidomimetics & Constrained Peptides: Used to introduce structural constraints and novel side-chain functionalities into peptide backbones to enhance stability and biological activity.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Bioconjugation & Probe Development: The reactive functional groups allow for its use in creating fluorescent probes or affinity labels for biochemical studies.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective synthetic routes.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic chemistry and chemical biology.

Basic Information

Product Name	(R)-4-(Indol-3-Yl)-β-Homoalanine
CAS No.	736131-01-4
Molecular Formula	C₁₃H₁₄N₂O₂
Molecular Weight	230.26 g/mol
Synonyms	(R)-4-(1H-Indol-3-yl)-2-aminobutanoic acid; (R)-4-(Indol-3-yl)-homoalanine; (R)-3-(2-Amino-3-carboxypropyl)indole; (R)-α-Amino-4-(indol-3-yl)butyric acid; (R)-Homoalanine, 4-(indol-3-yl)-; (R)-4-(3-Indolyl)-β-homoalanine; (R)-2-Amino-4-(1H-indol-3-yl)butanoic acid
EINECS	Contact for details

Quality Control

Our (R)-4-(Indol-3-Yl)-β-Homoalanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.