Description

3H-Pyrrolizin-3-One,1,2,5,7A-Tetrahydro-1-Methyl-,(1R,7Ar)-Rel-(9Ci) is a high-purity, stereochemically defined heterocyclic compound identified by CAS number 733751-77-4. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates targeting a range of diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Acts as a precursor in the development of new pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and protein function.
• Academic Research: Provides a valuable compound for methodological studies in organic synthesis, particularly in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	3H-Pyrrolizin-3-One,1,2,5,7A-Tetrahydro-1-Methyl-,(1R,7Ar)-Rel-(9Ci)
CAS No.	733751-77-4
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	(1R,7aR)-rel-1,2,5,7a-Tetrahydro-1-methyl-3H-pyrrolizin-3-one; 1-Methyl-1,2,5,7a-tetrahydro-3H-pyrrolizin-3-one (rel-(1R,7aR)-); rel-(1R,7aR)-1-Methyl-1,2,5,7a-tetrahydro-3H-pyrrolizin-3-one; Pyrrolizin-3-one derivative; Advanced heterocyclic intermediate; Chiral pyrrolizine scaffold.
EINECS	Contact for details

Quality Control

Our 3H-Pyrrolizin-3-One,1,2,5,7A-Tetrahydro-1-Methyl-,(1R,7Ar)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.