Description

3-Indolizinecarbonitrile,2-Fluoro-(9Ci) is a specialized fluorinated indolizine derivative, a high-value building block in advanced organic synthesis. Its core value lies in enabling the precise introduction of both the indolizine scaffold and a nitrile functional group, which are critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorinated indolizine structure can enhance bioavailability and environmental stability.
• Material Science: Acts as a monomer or functional additive in the creation of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probe Development: Utilized to create fluorescent tags or molecular probes for studying biological processes and enzyme mechanisms.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	3-Indolizinecarbonitrile,2-Fluoro-(9Ci)
CAS No.	733054-10-9
Molecular Formula	C10H5FN2
Molecular Weight	172.16 g/mol
Synonyms	2-Fluoro-3-indolizinecarbonitrile; 2-Fluoroindolizine-3-carbonitrile; 3-Cyano-2-fluoroindolizine; 2-Fluoro-1-azaindole-3-carbonitrile; 2-Fluoroindolizine-3-carbonitrile (9CI); 733054-10-9; 2-Fluoro-3-cyanoindolizine
EINECS	Contact for details

Quality Control

Our 3-Indolizinecarbonitrile,2-Fluoro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.