Description

7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-4-(Nitrooxy)Butyl Ester, 6-Heptenoic Acid is a specialized, high-purity synthetic intermediate with a complex molecular architecture. This compound is of significant value in advanced pharmaceutical research and development, particularly for its potential role in creating novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique indole and nitrooxy ester functionalities.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes in pilot plants and commercial manufacturing.
• Bioconjugation & Prodrug Synthesis: Potential use in designing prodrugs or targeted drug delivery systems leveraging its ester and reactive groups.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in regulatory submissions.
• Custom Synthesis Starting Material: Used by fine chemical manufacturers for producing custom-designed compounds for client-specific research programs.

Basic Information

Product Name	7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-4-(Nitrooxy)Butyl Ester, 6-Heptenoic Acid
CAS No.	733034-56-5
Molecular Formula	C30H35FN2O7
Molecular Weight	554.61 g/mol
Synonyms	6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-4-(nitrooxy)butyl ester; 733034-56-5; 4-(Nitrooxy)butyl 7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate; 1H-Indole-6-heptenoic acid derivative; Isopropyl-4-fluorophenyl indole nitrooxy ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-4-(Nitrooxy)Butyl Ester, 6-Heptenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen in a desiccated environment. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.