Description

2,5-Diazabicyclo[2.2.1]Heptane-2-Ethanol,(1S,4S)-(9Ci) is a high-purity, chiral bicyclic diamine derivative with significant utility as a sophisticated building block in organic synthesis. This compound matters for its role as a key chiral ligand and intermediate in the development of asymmetric catalysts and active pharmaceutical ingredients (APIs). Pharmaceutical research and fine chemical synthesis companies need this material to enable complex, stereoselective transformations critical for producing novel therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand: Serves as a precursor for the development of proprietary chiral ligands used in metal-catalyzed asymmetric synthesis, enabling high enantioselectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals where its rigid bicyclic structure imparts specific stereochemical and conformational properties.
• Agrochemical Research: Used in the research and development of advanced, enantiomerically pure agrochemicals to enhance efficacy and reduce environmental impact.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, particularly in studies focused on new C-N bond formation and cyclization reactions.

Basic Information

Product Name	2,5-Diazabicyclo[2.2.1]Heptane-2-Ethanol,(1S,4S)-(9Ci)
CAS No.	732236-94-1
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	(1S,4S)-2-(2-Hydroxyethyl)-2,5-diazabicyclo[2.2.1]heptane; (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane-2-ethanol; 2,5-Diazabicyclo[2.2.1]heptane-2-ethanol, (1S,4S)-; (1S,4S)-2-(Hydroxyethyl)-2,5-diazabicyclo[2.2.1]heptane; (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane-2-ethanol (9CI); (1S,4S)-2-(2-Hydroxyethyl)-2,5-diazabicyclopentane
EINECS	Contact for details

Quality Control

Our 2,5-Diazabicyclo[2.2.1]Heptane-2-Ethanol,(1S,4S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.