Description

Indolizine, 5,6-Dihydro-5-(1-Methylethyl)-, (5S)- (9Ci) is a chiral, saturated indolizine derivative characterized by its specific stereochemistry at the 5-position. This compound serves as a valuable and versatile chiral building block or intermediate in advanced organic synthesis, particularly for the construction of complex nitrogen-containing heterocycles. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a component for creating novel organic electronic materials or functional polymers.
• Academic & R&D Laboratories: Employed in methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	Indolizine, 5,6-Dihydro-5-(1-Methylethyl)-, (5S)- (9Ci)
CAS No.	731854-03-8
Molecular Formula	C11H17N
Molecular Weight	163.26 g/mol
Synonyms	(5S)-5,6-Dihydro-5-(1-methylethyl)indolizine; (5S)-5-Isopropyl-5,6-dihydroindolizine; 5,6-Dihydro-5-(1-methylethyl)-, (5S)-Indolizine; 5-Isopropyl-5,6-dihydroindolizine (S-enantiomer); (S)-5-Isopropyl-5,6-dihydroindolizine; 731854-03-8; Indolizine, dihydro-5-(1-methylethyl)-, (5S)-
EINECS	Contact for details

Quality Control

Our Indolizine, 5,6-Dihydro-5-(1-Methylethyl)-, (5S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.