Description

2-(Chloromethyl)Indolizine-1-Carbonitrile is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique indolizine scaffold, functionalized with both a chloromethyl group and a nitrile, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting bioactive heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a precursor for the synthesis of specialized organic electronic materials and functional dyes.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-(Chloromethyl)Indolizine-1-Carbonitrile
CAS No.	731821-82-2
Molecular Formula	C10H7ClN2
Molecular Weight	190.63 g/mol
Synonyms	1-Cyano-2-(chloromethyl)indolizine; 2-(Chloromethyl)-1-cyanoindolizine; 1-CN-2-CH2Cl-Indolizine; Indolizine-1-carbonitrile, 2-(chloromethyl)-; 731821-82-2; 2-Chloromethyl-1-cyanoindolizine
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)Indolizine-1-Carbonitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.