Description

3,4-Dihydroisoquinolin-2(1H)-Ylacetic Acid Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its core value lies in its role as a versatile synthon for constructing complex nitrogen-containing heterocycles, which are prevalent in active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of isoquinoline-based drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and oncology.
• Organic Synthesis Reagent: Used as a precursor for constructing complex polycyclic frameworks and fused heterocyclic systems in medicinal chemistry and material science.
• Agrochemical Research: Intermediate in the development of novel pesticides and herbicides with specific biological activity.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Academic & Contract Research: Essential material for method development and exploratory research in synthetic organic chemistry laboratories.

Basic Information

Product Name	3,4-Dihydroisoquinolin-2(1H)-Ylacetic Acid Hydrochloride
CAS No.	731810-79-0
Molecular Formula	C11H12ClNO2 • (x)HCl
Molecular Weight	Contact for details
Synonyms	2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)acetic acid hydrochloride; 1,2,3,4-Tetrahydroisoquinoline-2-acetic acid HCl; (1,2,3,4-Tetrahydro-2-isoquinolinyl)acetic acid hydrochloride; 2-Carboxymethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; DHIQAA-HCl; TIQAA-HCl
EINECS	Contact for details

Quality Control

Our 3,4-Dihydroisoquinolin-2(1H)-Ylacetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.