Description

Methyl 6-n-Boc-Aminoindole-4-Carboxylate is a high-purity, protected indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Peptidomimetic Synthesis: Used to incorporate indole-based structures into peptide backbones to enhance stability and biological activity.
• Combinatorial Chemistry: Serves as a versatile scaffold in the generation of diverse compound libraries for high-throughput screening.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Material Science: Potential building block for advanced organic electronic materials and functional polymers.
• Academic & Contract Research: Used in university and CRO laboratories for fundamental research in heterocyclic chemistry and method development.

Basic Information

Product Name	Methyl 6-n-Boc-Aminoindole-4-Carboxylate
CAS No.	731810-56-3
Molecular Formula	C16H20N2O4
Molecular Weight	304.34 g/mol
Synonyms	Methyl 6-[(tert-butoxycarbonyl)amino]-1H-indole-4-carboxylate; 6-(Boc-amino)-1H-indole-4-carboxylic acid methyl ester; Methyl 6-(Boc-amino)indole-4-carboxylate; 1H-Indole-4-carboxylic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Boc-6-Aminoindole-4-carboxylic Acid Methyl Ester; 6-N-Boc-Aminoindole-4-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 6-n-Boc-Aminoindole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.