Description

2-Bromo-3-(4-Fluorophenyl)-1-Propene is a versatile halogenated organic building block characterized by its bromoalkene and fluorinated aromatic functionalities. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures through cross-coupling and cycloaddition reactions. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the bioactivity of the fluorophenyl group.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the preparation of novel organometallic complexes and chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	2-Bromo-3-(4-Fluorophenyl)-1-Propene
CAS No.	731773-10-7
Molecular Formula	C9H8BrF
Molecular Weight	215.06 g/mol
Synonyms	1-Bromo-2-(4-fluorophenyl)propene; 2-Bromo-1-(4-fluorophenyl)-1-propene; 3-(4-Fluorophenyl)-2-bromoprop-1-ene; (4-Fluorophenyl)-2-bromopropene; 2-Bromo-3-(p-fluorophenyl)propene; 1-Propene, 2-bromo-3-(4-fluorophenyl)-; p-Fluorophenyl-2-bromopropene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(4-Fluorophenyl)-1-Propene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from strong acids and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.